Research

Publications

Buckley M, Terwagne C, Ganner A, …, Diederichs SNeumann-Haefelin E, Turajlic S, Ivakine EA, Findlay GM. Saturation genome editing maps the functional spectrum of pathogenic VHL alleles. Nat Genet (2024). Arnold F, Kupferschmid L, Weissenborn P, …, Zareba P, Sagar, Rogg M, Schell CTanriver Y. Tissue-resident memory T cells break tolerance to renal autoantigens and orchestrate immune-mediated nephritis. Cell Mol Immunol (2024). Talvard-Balland N, Braun LM, Dixon KO, …, Köttgen A, …, Börries M, …, Becher B, Köhler N, Wertheimer T, Kuchroo VK, Zeiser R. Oncogene induced TIM-3 ligand expression dictates susceptibility to anti-TIM-3 therapy in mice. J Clin Invest (2024). Monteiro-Martins S, Sterenborg RBTM, Borisov O, Scherer N, Cheng Y, Medici M, Köttgen A, Teumer A. New insights into the hypothalamic-pituitary-thyroid axis: a transcriptome- and proteome-wide association study. Eur Thyroid J (2024). Fröhlich K, Fahrner M, Brombacher E, Seredynska A, Maldacker M, Kreutz C, Schmidt A, Schilling O. Data-independent acquisition: A milestone and prospect in clinical mass spectrometry-based proteomics. Mol Cell Proteomics (2024). Moeed A, Thilmany N, Beck F, …, Börries M, …, Zanetta P, Schell C, Schwemmle M, Weber A, Häcker G. The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection. Cell Death Differ (2024). Yeo WJ, Surapaneni AL, Hasson DC, Schmidt IM, Sekula PKöttgen A, …, Vasan RS, Kimmel PL, Coresh J, Grams ME, Schlosser P. Serum and Urine Metabolites and Kidney Function. J Am Soc Nephrol (2024). Steinbrenner I, Schultheiss UT, Bächle H, …, Schlosser P, …, Schaeffner E, Eckardt KU, Köttgen ASekula P, GCKD Ivestigators. Associations of Urine and Plasma Metabolites with Kidney Failure and Death in a CKD Cohort. Am J Kidney Dis (2024). Kessler S, Burke B, Andrieux G, …, Börries M, Rizzi M, Beer M, Schwemmle M, Reuther P, Schountz T, Ciminski K. Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level. Nat Commun (2024). Leroy C, Lang K, Spitz D, …, Kayser S, Helmstädter M, Walz G, Ulbrich MH, Hermle T. Linking Basement Membrane and Slit Diaphragm in Drosophila Nephrocytes. J Am Soc Nephrol (2024). Vinnakota JM, Biavasco F, Schwabenland M, …, Börries M, …, Subklewe M, von Baumgarten L, Gill S, Prinz M, Zeiser R. Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nat Cancer (2024). Kellner E, Sekula P, Lipovsek J, …, Bamberg F, Büchert M, Reichardt W, Reisert M, Köttgen A. Imaging Markers Derived From MRI-Based Automated Kidney Segmentation—an Analysis of Data From the German National Cohort (NAKO Gesundheitsstudie). Dtsch Ärztebl Int (2024). Rodriguez-Hernandez Z, Gorski M, Tellez-Plaza M, Schlosser PWuttke M. metaGWASmanager: a toolbox for an automated workflow from phenotypes to meta-analysis in GWAS consortia. Bioinformatics (2024). Schlosser P, Surapaneni AL, Borisov O, …, Köttgen A, Rhee EP, Coresh J, Grams ME, CRIC Study Investigators & CKD Biomarkers Consortium. Association of Integrated Proteomic and Metabolomic Modules with Risk of Kidney Disease Progression. J Am Soc Nephrol (2024). Topitsch A, Halstenbach T, Rothweiler R, Fretwurst T, Nelson K, Schilling O. Mass Spectrometry-Based Proteomics of Poly(methylmethacrylate)-Embedded Bone. J Proteome Res (2024). Schneider J, Mitschke J, Bhat M, Vogele D, Schilling O, Reinheckel T, Heß L. Cathepsin D inhibition during neuronal differentiation selectively affects individual proteins instead of overall protein turnover. Biochimie (2024).