Publications

Smit RAJ, Wade K, Hui Q, …, Wuttke M, …, Timpson NJ, Hirschhorn JN, Sun YV, Berndt SI, Loos RJF. Polygenic prediction of body mass index and obesity through the life course and across ancestries. Nat Med (2025). Schrecker M, Son Y, Planells-Cases R, Kar S, Vorobeva V, Schulte U, Fakler B, Jentsch TJ, Hite RK. Structural basis of ClC-3 transporter inhibition by TMEM9 and PtdIns(3,5)P2. Nat Struct Mol Biol (2025). Chatterjee S, Rückert T, Martin I, …, Andrieux G, Cabezas-Wallscheid N, Börries M, Prinz M, Zeiser R. Gut microbiota-derived TMAVA is a modulator of acute CNS-GVHD. J Exp Med (2025). Schlosser P, Köttgen A. A multiomic resource to interpret genetic associations with kidney function. Kidney Int (2025). Chaves AFA, de Barros BCSC, Cosenza-Contreras M, …, Pinter N, Schmid M, Santoro ML, Schilling O, Serrano SMT. Signatures of the systemic effects of a snake venom and antivenom: multiomics profiling of the kidney pathology. Mol Cell Proteomics (2025). Xie W, Franz H, Yakulov TA. Evaluating In-Hospital Arrhythmias in Critically Ill Acute Kidney Injury Patients: Predictive Models, Mortality Risks, and the Efficacy of Antiarrhythmic Drugs. J Clin Med (2025). Runge S, von Zedtwitz S, Maucher AM, …, Schell C, Boerries M, Strowig T, Andrieux G, Hild B, Rosshart SP. Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype. Nat Commun (2025). Peighambari A, Huang H, Metzger P, Adlesic M, …, Köttgen A, Schell C, …, Zeiser R, Heikenwalder M, Höfflin R, Boerries M, Frew I. Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance. Sci Rep (2025). Teng YH, Appiah B, Andrieux G, …, Hofmann AS, Ku M, Beyes S, Boerries M, Hecht A. TGF-β signaling redirects Sox11 gene regulatory activity to promote partial EMT and collective invasion of oncogenically transformed intestinal organoids. Oncogenesis (2025). Konwar S, Schroda S, Rogg M, …, Grosse R, Schell C, Vidal S, Liu X, Gorzelanny C, Tschongov T, Häffner K. Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis. J Clin Invest (2025). Wolff JM, Lang K, Chen M, …, Walz G, Abed A, Gerstner L, Bahar S, Ulbrich MH, Hermle T. Transgenic human nephrin in Drosophila nephrocytes facilitates variant analysis. Kidney Int (2025). Ganner A, Ferrara AM, Sekula P, …, Walz MK, Köttgen A, Eng C, Neumann HPH, Neumann-Haefelin E. Genotype-specific neoplastic risk profiles in patients with VHL disease. Endocr Relat Cancer (2025). Berns H, Weber D, Haas M, Bakey Z, Brislinger-Engelhardt MM, Schmidts M, Walentek P. A homozygous human WNT11 variant is associated with laterality, heart and renal defects. Dis Model Mech (2025). Schlösser RM, Krumbach F, Corrales E, …, Boerries M, Becker K, Knüchel R, Garczyk S, Lüscher B. Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal-like and malignant urothelial cells. Mol Oncol (2025). Planells-Cases R, Vorobeva V, Kar S, Schmitt FW, Schulte U, Schrecker M, Hite RK, Fakler B, Jentsch TJ. Endosomal chloride/proton exchangers need inhibitory TMEM9 β-subunits for regulation and prevention of disease-causing overactivity. Nat Commun (2025). Fernandez-Orth J, Koyunlar C, Weiss JM, …, Boerries M, Touw IP, Niemeyer C, Erlacher M, de Pater E. Hematological phenotypes in GATA2 deficiency syndrome arise from aging maladaptation to proliferation and somatic events. Blood Adv (2025).