Publications

Zeyer KA, Tholen S, Schilling O, Gerling L, Morath M, Kölker S, Nyström A, Spiekerkoetter U, Schumann A. Transforming Growth Factor-β-Mediated Fibrotic Remodeling Drives Chronic Kidney Disease in Methylmalonic Aciduria and Propionic Aciduria-Identification of a New Therapeutic Target. J Inherit Matab Dis (2025). Busch T, Neubauer B, Sediq S, Zeisler PC, Tholen S, Schilling O, Westermann L, Köttgen M. SDF2 and SDF2L1 are essential co-factors of DNAJB11 for Polycystin-1 processing. J Biol Chem (2025). Monteiro-Martins S, Li Y, Borisov O,…, Ott E,…, Kiryluk K, Sekula P, reisert M, Köttgen A. Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function. Kidney Int (2025). Moser D, Lang K, Birtasu AN, Grahammer F, Helmstädter M, Scheffer MP, Hermle T, Frangakis AS. The slit diaphragm in Drosophila exhibits a bilayered, fishnet architecture. Nat Commun (2025). Stawarski M, Ulrich D, Reinartz S,…,Lütjens R, Gassmann M, Fakler B, Barkat TR, Bettler B. Normalization of network activity in an epilepsy model with a constitutively active GABBR2 variant. Brain (2025). Bahat A, Milenkovic D, Cors E,…, Schell C, Muylaert I, Larsson E, Nolte H, Falkenberg M, Langer T. Ribonucleotide incorporation into mitochondrial DNA drives inflammation. Nature (2025). Chubanov V, Grimm C, Hill K,…, Köttgen M, Storch U, Schnitzler MMY, Kudrina V, Erbacher A, Gudermann T. Physiological functions and pharmacological targeting of transient receptor potential channels. Pharmacol Rev (2025). Epting D, Devane J, Mertes R, Kayser S, Helmstädter M, Metzger P, Boerries M, Bergmann C, Ott E. Tulp3 deficiency results in ciliopathy phenotypes during zebrafish embryogenesis. Sci Rep (2025) Epting D, Braun DA, Decker E, Ott E, Eisenberger T, Bachmann N, Nedvetsky P, Krahn MP, Hildebrandt F, Bergmann C. PATJ deficiency leads to cystic kidney disease and related ciliopathies. HGG Adv (2025) Nsangou YAN, Halder RK, Uddin A,…, Schultheiss UT,…,Kosch R, Altenbuchinger M, Zacharias HU, Kastenmüller G, Dönitz J. Use of Client-Side Machine Learning Models for Privacy-Preserving Healthcare Predictions – A Deployment Case Study. Stud Health Technol Inform (2025). Sekula P, Steinbrenner I, Schultheiss UT,…, Cadarette SM, Riley RD, Collins GS, Sauerbrei W, Gail MH. Design aspects for prognostic factor studies. BMJ Open (2025). Constantin CE, Schmidt B, Schwarz Y,…, Kulik A, Bruns D, Schulte U, Rieger H, Fakler B. Ca2+-pumping by PMCA-neuroplastin complexes operates in the kiloHertz-range. Nat Commun (2025). Vinayagam D, Sitsel O, Schulte U, Constantin CE, Oosterheert W, Prumbaum D, Zolles G, Fakler B, Stefan Raunser. Molecular mechanism of ultrafast transport by plasma membrane Ca2+-ATPases. Nature (2025). Molnar C, Rajak J, Weiss JM,…, Börries M,…, Bohler S, Erlacher M. PUMA-induced apoptosis drives bone marrow failure and genomic instability in telomerase-deficient mice. Cell Death Differ (2025). Feilen T, Rogg M, Andreev G,…, Neumann-Haefelin E, Ganner A, Grabbert M, Schell C, Schilling O. Proteomic characterization of the pseudocapsule of clear cell renal cell carcinoma in VHL disease reveals a distinct microenvironment at the tumor boundary zone. Neoplasia (2025). Eckert P, Nöller M, Müller M…, Zhao D, Xie W, Boerries M, Walz G, Yakulov TA. Targeting GLP-1 Signaling Ameliorates Cystogenesis in a Zebrafish Model of Nephronophthisis. Int J Mol Sci (2025).