Research

Publications

Runge S, von Zedtwitz S, Maucher AM, …, Schell CBoerries M, Strowig T, Andrieux G, Hild B, Rosshart SP. Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype. Nat Commun (2025). Peighambari A, Huang H, Metzger P, Adlesic M, …, Köttgen ASchell C, …, Zeiser R, Heikenwalder M, Höfflin R, Boerries MFrew I. Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance. Sci Rep (2025). Teng YH, Appiah B, Andrieux G, …, Hofmann AS, Ku M, Beyes S, Boerries M, Hecht A. TGF-β signaling redirects Sox11 gene regulatory activity to promote partial EMT and collective invasion of oncogenically transformed intestinal organoids. Oncogenesis (2025). Konwar S, Schroda S, Rogg M, …, Grosse RSchell C, Vidal S, Liu X, Gorzelanny C, Tschongov T, Häffner K. Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis. J Clin Invest (2025). Wolff JM, Lang K, Chen M, …, Walz G, Abed A, Gerstner L, Bahar S, Ulbrich MH, Hermle T. Transgenic human nephrin in Drosophila nephrocytes facilitates variant analysis. Kidney Int (2025). Ganner A, Ferrara AM, Sekula P, …, Walz MK, Köttgen A, Eng C, Neumann HPH, Neumann-Haefelin E. Genotype-specific neoplastic risk profiles in patients with VHL disease. Endocr Relat Cancer (2025). Berns H, Weber D, Haas M, Bakey Z, Brislinger-Engelhardt MMSchmidts MWalentek P. A homozygous human WNT11 variant is associated with laterality, heart and renal defects. Dis Model Mech (2025). Schlösser RM, Krumbach F, Corrales E, …, Boerries M, Becker K, Knüchel R, Garczyk S, Lüscher B. Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal-like and malignant urothelial cells. Mol Oncol (2025). Planells-Cases R, Vorobeva V, Kar S, Schmitt FW, Schulte U, Schrecker M, Hite RK, Fakler B, Jentsch TJ. Endosomal chloride/proton exchangers need inhibitory TMEM9 β-subunits for regulation and prevention of disease-causing overactivity. Nat Commun (2025). Fernandez-Orth J, Koyunlar C, Weiss JM, …, Boerries M, Touw IP, Niemeyer C, Erlacher M, de Pater E. Hematological phenotypes in GATA2 deficiency syndrome arise from aging maladaptation to proliferation and somatic events. Blood Adv (2025). Andreev G, Vollmer T, Zirngibl M, Werner M, Grabbert M, Schilling O, Rogg M, Schell C. Spatial correlation of the extracellular matrix to immune cell phenotypes in the tumor boundary of ccRCC revealed by cyclic immunohistochemistry. Lab Invest (2025). Wiegel J, Helmstädter M, Walz GBergen M. Spontaneous Calcium Bursts Organize the Apical Actin Cytoskeleton of Multiciliated Cells. Int J Mol Sci (2025). Wess M, Rogg M, Gueib-Picard C, …, Feilen T, Andreev G, Werner M, Frew I, Grabbert M, Schilling OSchell C. Versatile roles of annexin A4 in clear cell renal cell carcinoma: Impact on membrane repair, transcriptional signatures, and composition of the tumor microenvironment. iScience (2025). Walentek P. Mucociliary cell type compositions – bridging the gap between genes and emergent tissue functions. Cells Dev (2025). Tschongov T, Konwar S, Kleindienst J, Dabrowska-Schlepp P, Busch A, Schaaf A, Schell C, Rogg M, Häffner K. Effective long-term treatment with moss-produced factor H by overcoming the antibody response in a mouse model of C3G. Front Immunol (2025). Elcin-Guinot S, Lagies S, Avi-Guy Y, Neugebauer D, Huber TBSchell C, Kammerer B, Römer W. Lectin-Based Substrate Detection in Fabry Disease Using the Gb3-Binding Lectins StxB and LecA. Int J Mol Sci (2025).