Peggy Sekula

Current Position

Senior Researcher / Statistician

Academic Education

1999 - 2003

Diploma in Mathematics (Dipl-Math (FH)), Berlin

Advanced Qualifications

2020	Habilitation (PD), Faculty of Medicine, University of Freiburg
2012	Doctoral degree in Mathematics (Dr. rer. nat.) Faculty of Mathematics and Physics, University of Freiburg

Postgraduate Positions

2012 - present

Medical Center – University of Freiburg, Institute of Epidemiology und Prevention

Publications on CRC 1453 funding

Ganner A, Ferrara AM, Sekula P, …, Walz MK, Köttgen A, Eng C, Neumann HPH, Neumann-Haefelin E. Genotype-specific neoplastic risk profiles in patients with VHL disease. Endocr Relat Cancer (2025). Scherer N, Fässler D, Borisov O, Cheng Y, Schlosser P, Wuttke M, …, Sekula P, Hoppmann A, Schultheiss UT, …, Schmidts, Köttgen M, …, Grünert SC, Estrada K, Thiele I, Hertel J, Köttgen A. Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits. Nat Genet (2025). Butz E, Schultheiss UT, Sekula P. Modeling heterogeneity in the progression of chronic kidney disease. Nephrol Dial Transplant (2024). Yeo WJ, Surapaneni AL, Hasson DC, Schmidt IM, Sekula P, Köttgen A, …, Vasan RS, Kimmel PL, Coresh J, Grams ME, Schlosser P. Serum and Urine Metabolites and Kidney Function. J Am Soc Nephrol (2024). Steinbrenner I, Schultheiss UT, Bächle H, …, Schlosser P, …, Schaeffner E, Eckardt KU, Köttgen A, Sekula P, GCKD Ivestigators. Associations of Urine and Plasma Metabolites with Kidney Failure and Death in a CKD Cohort. Am J Kidney Dis (2024). Kellner E, Sekula P, Lipovsek J, …, Bamberg F, Büchert M, Reichardt W, Reisert M, Köttgen A. Imaging Markers Derived From MRI-Based Automated Kidney Segmentation—an Analysis of Data From the German National Cohort (NAKO Gesundheitsstudie). Dtsch Ärztebl Int (2024). Clotet-Freixas S, Zaslaver O, Kotlyar M, …, Sekula P, Steinbrenner I, Köttgen A, …, Jurisica I, Woo M, Scholey JW, Röst H, Konvalinka A. Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease. Sci Transl Med (2024). Kheirkhah A, Schachtl-Riess JF, Lamina C, Di Maio S, Koller A, …, Sekula P, …, Köttgen A, Eckardt KU, Kronenberg F. Meta-GWAS on PCSK9 concentrations reveals associations of novel loci outside the PCSK9 locus in White populations. Atherosclerosis (2023). Schlosser P, Scherer N, Grundner-Culemann F, Monteiro-Martins S, Haug S, …, Wuttke M, …, Köttgen M, …, Schmidts M, …, Schultheiss UT, …, Sekula P, Li Y, Köttgen A. Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine. Nat Genet (2023). Steinbrenner I, Yu Z, Jin J, Schultheiss UT, Kotsis F, …, Wuttke M, …, Chatterjee N, Sekula P, Köttgen A. A polygenic score for reduced kidney function and adverse outcomes in a cohort with chronic kidney disease. Kidney international (2022). Steinbrenner I, Sekula P, Kotsis F, von Cube M, Cheng Y, …, Eckardt KU, Schultheiss UT, GCKD investigators. Association of osteopontin with kidney function and kidney failure in chronic kidney disease patients: the GCKD study. Nephrol Dial Transplant (2022). Li Y, Cheng Y, Consolato F, Schiano G, Chong MR, …, Sekula P, Steinbrenner I, Schlosser P, …, Schultheiss UT, …, Wuttke M, …, Devuyst O, Rampoldi L, Köttgen A. Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases. JCI Insight (2022). Cheng Y, Li Y, Scherer N, Grundner-Culemann F, Lehtimäki T, …, Sekula P, Schultheiss UT; GCKD investigators. Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study. PLoS Genet (2022). Kotsis F, Schultheiss UT, Wuttke M, Schlosser P, Mielke J, …, Sekula P, Köttgen A, GCKD Investigators. Self-Reported Medication Use and Urinary Drug Metabolites in the German Chronic Kidney Disease (GCKD) Study. J Am Soc Nephrol (2021). Cheng Y, Schlosser P, Hertel J, Sekula P, Oefner PJ, …, Schmidts M; …, Thiele I, Li Y, Köttgen A. Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism. Nat Commun (2021).